ChemDoodle 2D

2D Chemical Drawing, Publishing and Informatics

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The best graphics in chemistry! Try a Free Trial Now ↗

Professional Quality, Affordable Prices

  • “I am a patent attorney and chemist who has become quite beholden to ChemDoodle, particularly the newest version (I've been around since Version 5 or 6, but this thing has gone from great for the price to amazing). Thank you and, indeed, great product!”
    Dinsmore & Shohl LLP
  • “What can I say, above and beyond!!!! ... we are actively recommending the product.”
    CS Regulatory Ltd
  • “I think your program is superior to ChemDraw.”
    Southern Illinois University Edwardsville
  • “ChemDoodle has been a godsend this year.”
    Holmdel High School
  • “Being a mac user I couldn't use chemsketch; found chemdoodle and love it, intuitive to use as well!”
    University of Nottingham
  • “ChemDoodle is an amazingly affordable alternative to ChemDraw. For a fraction of the price, I can get the functionality I need to communicate with my colleagues.”
    Dymax Corporation
  • “ChemDoodle really is a lifesaver - no other chemical structure drawing program on the Mac comes even close...”
    ENVIRON
  • “Opened my ChemDraw files nicely; intuitive interface. Very smooth operation.”
    Cornell University
  • “I loved the easy-to-use interface; it made drawing molecules and reactions quick and fun!”
    California Polytechnic State University, SLO
  • “This is one of the best chemical drawing programs I have ever used. It is really easy to navigate and create structures. Much better than competitive programs and does not seem bloated and slow.”
    Castech Laboratories LLC
  • “Chemdoodle is very user friendly. I liked the fact that I could draw chem equations easily and without much frustration. Great application.”
    South Texas College
  • “I really like the intuitive feel, not to mention all of the neat widgets, of this program! I've been on a hunt for new chemical drawing software ever since I left my last institution where we had a ChemDraw site license. I've only played around with this software for a couple of hours, but I can already tell that this program is well on its way to blowing all of the other contenders out of the water. Well done guys!”
    Lynchburg College
  • “I've been teaching organic chemistry for 22 years, and have seen a lot of chemical drawing programs. This one is exceptional and I will be recommending this one to my students!”
    Red Deer College
  • “The program is brilliant, very useful for showing NMR to my students.”
    The Royal Latin School
  • “Chemdoodle is excellent, amazing and just unbelievably cheaper than Chemdraw ultra. It is very useful I really liked it and I am going to recommend it to everyone.”
    University of Tasmania
  • “Thank you for giving us a great alternative to ChemDraw! I am using ChemDoodle exclusively now.”
    Temple University
  • “Many thanks for the quick response, and for a feature-rich piece of software that allows us at cash-strapped state schools to make the nice structures we remember from back when we had site licenses for chemdraw. ChemDoodle kicks butt, and I will spread the gospel to my colleagues!”
    University of Missouri, Kansas City
  • “Wow! ChemDoodle is such a fantastic chemical drawing software package. Easy to use and PACKED with features it is such a bargain compared to the alternatives. The interface is intuitive and the User Guide is easy to read (I especially enjoy it being a searchable pdf). I've recommended this software to colleagues and will continue to do so. The more features I learn how to use the more I like it! Superb job!”
    MBSU
  • “ChemDoodle is brilliant! w/ the search option, I can draw Taxol and predict its NMR in 30 secs.”
    Aachen University
  • “I am impressed by the beautiful graphics of this software, and the outstanding operability.”
    Tokyo University of Science
  • “I really love your software and so do my students. We also really like the iPhone app - use it a lot in the Organic Lab I teach.”
    University of St. Thomas
  • “I would strongly recommend ChemDoodle. I find it better than ChemDraw or ISISDraw.”
    Max-Planck Institute
  • “I am lost without ChemDoodle.”
    University at Buffalo
  • “Just want to say this is a great alternative to Chemdraw.”
    University of Leeds
  • “I love the program and the app. Goodbye ChemDraw...finally!”
    SUNY Oneonta
  • “It is impressive. I love it. Many thanks.”
    Coatesville VA Medical Center
  • “Thanks again for making this software available for Linux, you are doing a really good job and the Linux users really appreciate your effort.”
    Cranfield University
  • “The MolGrabber widget has already saved my life and the appearance styling features are outstanding for presentations... yeehaw :)”
    Herbological
  • “Beautiful program, congratulations!”
    L'Université de Genève
  • “I just wanted to say thank you for your excellent customer service and responsiveness. If only all software companies operated this way!”
    Texas A&M
  • “ChemDoodle is really great. In fact, I don't miss anything I know from ChemDraw.”
    Kantonsschule Freudenberg
  • “You really did a very good job with regard to v7. I would especially commend ChemDoodle 3D, which is georgeous, simple for use, great performance, well organized, smoothly working, with a lot features included. The overall picture is breathtaking.”
    Lek Pharmaceuticals D.D.
  • “My compliments on version 7. Much cleaner and the UI is more intuitive. This makes the features easy to navigate to, but they remain compartmentalized. The glassware drawings has always been a nice feature, and I am happy to see it has been expanded from the version 5 I used to have. I will give a presentation at my next department meeting, as the common mythology is that NOTHING is as good as ChemDraw. I believe this version will push the burden onto ChemDraw supporters to provide evidence as to what amazing feature it has that this package cannot go toe-to-toe with.”
    Monsanto Company

Main Features

ChemDoodle 2D contains thousands of chemistry features, helping you produce the highest quality graphics and saving you hours of work.

  • 2D Graphics
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    The best graphics in chemistry

    • Pixel Perfect

      We spend a very long time scrutinizing the graphics output in ChemDoodle. The software automatically orients bonds in the correct directions, merges bond strokes together, places attributes in the best locations and automatically makes smart decisions that lead to the most beautiful and appealing images. Of course, you can always override the software to your preference.

    • Fully Customizable

      Every component of the graphic is fully customizable. Whether you are looking to control bond widths, arrowhead sizes or shape transparency and color; you are in control.

    • 24 Bond Types

      Represent chemical structures with the widest range of chemical bonds avialable in any software tool. From standard integer bonds, to specialty bonds like ionic and covalent, you can accurately depict any structure. All of the bonds orient themselves and merge together for the most aesthetic graphics.

    • Bond Stroke Merging

      In other programs, you will see disconnects where bonds meet, or a heavy reliance on rounded bond ends. In ChemDoodle, all of the bonds merge together for the most aestheic figures.

    • Advanced Labels

      Formatted atom labels allow you to clearly represent chemical entities as text and create concise, professional graphics.

    • Full Unicode Support

      Any characters supported by your fonts are available over the entire unicode range. Quick access to chemically relevant symbols is provided through the Symbols widget.

    • Atomic Notations

      ChemDoodle is the only chemical drawing tool to contain superscript and subscript merge formatting in text fields to easily create atomic notations and other chemical text.

    • Attributes

      Render charges, radicals and electrons, dipole moments, asterisks, tags and custom attributes on your structures, with full control over how they render.

    • Orbitals

      Atomic and molecular orbital graphics are easily added to figures. These are completely customizable just like the rest of ChemDoodle, so you can control color, stroke styling, fill type and more!

    • Highlights

      Easily highlight parts of your structures for emphasis and attention.

    • Lewis Dot Structures

      ChemDoodle provides you with all the tools to build perfect figures of Lewis Dot Structures. Draw them yourself, or have ChemDoodle automatically create the Lewis Dot Structures for you!

    • Perspective Structures

      Easily create 3D effects in figures by using protruding and bold bonds. ChemDoodle will automatically merge their strokes for an optimal appearance. Bonds in the foreground will buffer intersecting bonds in the background.

    • Stroke Styling

      Choose from 7 different stroke styles to add a bit of character to your figures (Basic, Bristle, Brush, Charcoal, Scribble, Slant, Wobble). Perfect for use in group meetings and in presentations.

    • Arrows

      Standard arrows allow for reaction graphics, while Bézier arrows make for beautiful mechanism drawings.

    • Shapes

      Draw rectangles, ovals, arcs, lines, brackets, Bézier curves, rulers, and more. And of course, all of the shapes are fully stylable.

    • TLC Plates

      Draw thin layer chromatography plates using the TLC Canvas widget.

  • Drawing
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    A powerful interface to quickly complete your work

    • Intuitive Controls

      ChemDoodle’s drawing controls are made to clearly model the atoms and bonds they manage. Copious visual feedback is provided. There are also many options for customizing the drawing tools to your preference, including for accessibility concerns.

    • Measured Drawings

      ChemDoodle will help guide your drawing to create the most aesthetic figures using a feature we call the "Optimize Zone" for standard bond angles and lengths. Just move your mouse out of the zone to override it.

    • Chemical Labels

      In addition to the standard elemental labels, you can input any custom label you desire. ChemDoodle will automatically chemically interpret and format labels. You can also directly control text formatting. Labels can be expanded to full atom models and full atom models can be automatically collapsed into concise labels based on your abbreviation library or to a custom label.

    • Condensed Labels

      Shortcuts and compound labels like "COOH" and "Ph", as well as formulae can be expanded to quickly build and work with complex chemical structures.

    • Custom Element Color Sets

      In addition to the predefined Jmol, Rasmol, PyMOL and CDK color sets, you can also manually define your own elemntal color set to apply to molecule rendering.

    • Automatic Atom/Bond Tagging

      If you need to tag atoms or bonds by increments, ChemDoodle provides powerful tools to do this. Simply click on the atom or bond to tag them and the next tag is automatically incremented. Tag by alphabet, number, roman numeral or greek letter.

    • Auto-layout of Attributes

      ChemDoodle will automatically place your charges, radicals, stereocenter labels and other attributes for you in an aesthetic manner. You can override these decisions at any time by holding down and dragging the mouse during placement.

    • Arbitrary Ring and Crown Ethers

      In addition to standard ring tools and templates, ChemDoodle provides special arbitrary ring and crown ether tools for quickly building advanced ring systems.

    • Templates

      Quickly build structures using our built-in template libraries, or create your own templates. The Templates widget organizes the templates for you.

    • Carbon Nanotube Builders

      Several tools are provided to help you quickly build complex 3D geometries, including carbon nanotube and prism builders. Armchair, zigzag and chiral nanotubes can be built. Use the Rotate in 3D tool to change the 3D perspective of the drawn structure.

    • Structure Cleaning

      Complex algorithms have been implemented to automatically lay out chemical structures aesthetically. Select only part of a structure to clean only that part, leaving the remaining structure untouched.

    • Reactions

      Draw reactions with arrows. ChemDoodle contains an entire toolbar for the custom creation of any arrow graphic desired. Presets are also included for bold, retrosynthetic and other arrows. You can define reactants and products, and even have ChemDoodle layout the reaction for you aesthetically.

    • Database Lookup

      Search databases (PubChem, ChemSpider, ChemExper) for chemical structures and drag them right into your 3D scene using the MolGrabber widget.

    • and so much more...

      There are so many tools in ChemDoodle for working with chemical graphics, including alignment and distribution functions, bond adjustment features, action tracking, transforms and more.

  • IUPAC Naming
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    Industry leading IUPAC naming algorithms

    Accurate Language

    Our algorithms name molecules naturally and accurately, down to the character and formatting. If you find any problems, simply contact us with the structure so we can correct it.

    Broad Scope

    The entire history of the IUPAC nomenclature library is used in our development. The majority of the periodic table is handled.

    Customization

    Over 40 options for customizing how names are generated, or to switch between various IUPAC rules.

    Auto-updating Labels

    Display IUPAC names for your structures that automatically update as you draw them. You can even display IUPAC locants on your structures to help with descriptions.

    Name to Structure

    IUPAC names can be parsed into structure representations as well.

  • Cheminformatics
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    Chemical intelligence essential to every chemist

    • Implicit Hydrogens

      Implicit hydrogens will be added for you to your drawings. You have the ability to turn them off for single atoms, globally or override them as appropriate.

    • Bond Detection

      Automatically detect bonds in chemical files that don't contain bond data.

    • Ring Perception

      Calculate and depict ring systems in your structures, including the Smallest Set of Smallest Rings (SSSR), the Euler Facet Ring Set, and the Hanser Ring Set.

    • Aromaticity

      Detect the aromaticity and anti-aromaticity of your rings and display the number of pi electron contributors. You can also force aromatic ring recognition using all resonance bonds. Tools are available to switch your figures between Kekulé, delocalized and circle forms.

    • Stereochemistry

      Perceive stereochemistry for drawn 2D structures. CIP stereochemistry is determined for chiral centers and double bonds. Common cis/trans stereochemistry can also be determined for double bonds.

    • 3D Coordinate Generation

      Generate 3D coordinates for your drawn structures using a template method or Universal Force Field (UFF) optimization.

    • Descriptors

      Calculate dozens of descriptors for structures, including masses, formulae, volumes, physical properties, topological indexes, counts, bioactivity filters and more.

    • Elemental Analysis

      Use the Elemental Analysis widget to calculate molecular masses, elemental analysis and isotopic distributions for structures as you draw them. Select entire complexes to calculate bulk properties.

    • Chemical Warnings

      ChemDoodle will double check your work for you and notify you when it finds chemistry issues, such as overvalanced atoms, or incorrectly drawn stereocenters.

    • References

      All of the resources we use to develop the algorithms in ChemDoodle or the choices we make for the software are documented in the Help menu. This way you can evaluate the quality of our work.

  • Spectroscopy
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    Easily create figures with both structures and spectra

    JCAMP-DX Format

    Read mass spectrometry (MS), nuclear magnetic resonance spectroscopy (NMR), infrared spectroscopy (IR) and other spectra from JCAMP-DX files. Multiple spectra are also recognized from the advanced JCAMP NTUPLES specification.

    Editing

    Completely edit the domain and range perspectives for your spectra. Include integration lines and grids. Format titles and then add annotations with shape tools.

    Simulation

    Simulate both 1H and 13C NMR spectroscopy as well as mass spectrum isotopic distributions. The NMR SignalSeek widget will also provide you with structure-spectrum correlations and further insight into the simulation. You can completely customize the settings for the simulations. Fine tune your analysis with the Multiplet Tool, which provides powerful functions for simulating and multiplet patterns.

    Mass Fragmentation Tools

    Use simple tools to quickly split bonds and calculate molecular masses for the fragments.

  • Vector Art
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    Hand-drawn scientific vector art libraries are included

    Laboratory Art

    Hundreds of different, hand-drawn, glassware images and other laboratory art are included to create very complex laboratory setups. Find helpful graphics, including laboratory appliances and safety sybols. Liquid fill colors can be controlled. Use thick Bézier curves for tubing.

    BioArt

    Full color and skillfully drawn vector graphics for illustrating cells, anatomy, animals, space and more.

    Infinitely Scalable

    The vector art is fully scalable, so each image can be resized or printed without any loss of resolution, leading to the most professional diagrams.

  • Publishing
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    Maximize your visibility with ChemDoodle's publishing features

    • Style Sheets

      ChemDoodle provides a number of predefined chemical style sheets to create styled graphics specifically for certain journals, including Nature and ACS Document 1996. You can also create and share your own style sheets to make creating books and other projects easier when groups are involved.

    • Chemical Files

      Read and write many popular chemical file types for working with the applications you use:

      ACD/ChemSketch Documents (.sk2), ChemDoodle Documents (.icl), ChemDoodle 3D Scenes (.ic3), ChemDoodle Javascript Data (.cwc.js), CambridgeSoft ChemDraw Exchange (.cdx), CambridgeSoft ChemDraw XML (.cdxml), Crystallographic Information Format (.cif), CHARMM CARD File (.crd), ChemAxon Marvin Document (.mrv), Chemical Markup Language (.cml), Daylight SMILES (.smi, .smiles), IUPAC InChI (.inchi), IUPAC JCAMP-DX (.jdx, .dx), ISIS Sketch File (.skc), ISIS Sketch Transportable Graphics File (.tgf), MDL MOLFiles, both V2000 and V3000 connection tables (.mol, .mdl), MDL SDFiles (.sdf, .sd), MDL RDFiles (.rdf, .rd), MDL RXNFiles, both V2000 and V3000 connection tables (.rxn), MMI SketchEl Molecule (.el), Molinspiration JME String (.jme), RCSB MacroMolecular Transmission Format (.mmtf), RCSB Protein Data Bank Files (.pdb, .ent), Schrödinger MacroModel (.mmd, .mmod), Schrödinger Maestro (.mae), Standard Molecular Data (.smd), Tripos Mol2 (.mol2, .ml2, .sy2), Tripos Sybyl Line Notation (.sln), Beilstein ROSDAL (.ros), XYZ Files (.xyz)

    • Line Notations

      Quickly analyze chemical line notations from websites and generate them for searches using the Line Notation Pad widget.

    • Bitmap (Raster, Pixel) Images

      Write a large number of bitmap (also known as raster or pixel) images for use with other applications. Some formats have additional options, such as controlling output resolution in PNG, JPEG, and TIFF images.

      1. CompuServ Graphics Interchange Format {.gif}
      2. Joint Photographic Experts Group {.jpg, .jpeg, .jpe, .jfif, .jfi, .jif}
      3. Microsoft Bitmap {.bmp, .dib}
      4. Portable Network Graphics {.png}
      5. Tagged Image File Format {.tiff, .tif}
      6. UNIX Portable PixMap {.ppm, pnm, pbm, pgm}
      7. Wireless Bitmap {.wbmp}

    • Scalable Vector Graphics

      Write a large number of vector graphics formats for use with other graphics applications when scalability is required. Most of the vector formats allow for text to shape conversion (compatibility) or preserving text output (for future editing, such as in LaTeX document creation). Most of the vector formats also allow embedding of chemical data to be recovered later.

      1. Adobe Portable Document Format {.pdf}
      2. Encapsulated Postscript {.eps, .epi, .epsi, .epsf}
      3. Macintosh Vector Pict {.pict}
      4. OpenDocument Graphics {.odg}
      5. Web Scalable Vector Graphics {.svg, .svgz}
      6. Windows Enhanced Metafile {.emf}

    • Web Components

      Produce 2D ChemDoodle Web Components, which are high-quality, interactive, HTML5 components for websites and web apps that work in Microsoft Edge, Mozilla Firefox, Google Chrome, Apple Safari and Opera, and even on Mobile Safari on iOS and Chrome for Android.

    • Twitter Integration

      Quickly tweet your selected content from ChemDoodle.

  • Universality
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    Regardless of what technologies you need, ChemDoodle is there

    • Operating Systems

      Fully supported on Windows, macOS and Linux.

    • High DPI Support

      Full support for high resolution displays, such as Retina Macs and the Microsoft Surface Pro.

    • Accessibility

      Control interface colors, interface font sizes, define cursors and a cursor left-handed and right-handed mode make it comfortable for most users to use the software. You can also fully define all of the menu item accelerators (except the ones forced by the operating system) and tool shortcuts.

    • Word Processors

      Paste scalable vector graphics into your favorite word processors, including Microsoft Office, Apple iWork and OpenOffice.

    • Round-trip Editing

      Round-trip editing allows you to insert content into 3rd party applications, and then place that same content back into ChemDoodle from that 3rd party application for further editing. Round-trip editing is supported on Windows through OLE, macOS via PDF and on Linux with OpenOffice.

      NOTE: It takes two applications to work together for round trip editing. While ChemDoodle provides functionality for round trip editing, the other application you want to round trip with may not support round trip editing. Other applications that do support round trip editing may remove round trip editing functionality at any time and without the consent of iChemLabs.

    • Quicklook Plugin

      A Quicklook plugin for macOS allows you to preview all of the chemical formats ChemDoodle understands conveniently in Finder. Not on Mac? No worries, ChemDoodle’s file chooser contains previews on all operating systems.

    • Search for Structures

      Search your computer and attached storage devices for chemical structures using the Search widget.

    • Browsers

      Produce interactive HTML5 components that work in Microsoft Edge, Mozilla Firefox, Google Chrome, Apple Safari and Opera, and even on Mobile Safari on iOS and Chrome for Android.

    • Mobile Devices

      A ChemDoodle license includes access to our ChemDoodle Mobile app companion for iOS (iPod/iPhone/iPad), Android and other mobile devices.

    • 3rd Party Integration

      ChemDoodle works with several partners to help you improve your workflow. These partners include databases like PubChem, ChemExper and ChemSpider, ELNs such as LabArchives and social networking services like Twitter.

    • Continuously Developed

      We are always adding new features, and our customers continuously enjoy new updates with great new innovative solutions and tools that they have requested. Your license entitles you to all updates.

Screenshots

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Windows interface (v9, Windows 10, high-DPI Surface Pro)
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macOS interface (v9, High Sierra, Retina)
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Linux interface (v9, Ubuntu 17.10)
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Paste scalable vector graphics into and round trip editing with Microsoft Office (Windows, Mac OS X) see features
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Paste scalable vector graphics into and round trip editing with Apple iWork and Microsoft Office (Mac OS X) see features
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Paste scalable vector graphics into and round trip editing with OpenOffice and LibreOffice (Linux) see features
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ChemDoodle contains dozens of options to control IUPAC naming output
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ChemDoodle works with ChemDoodle 3D (included with your ChemDoodle license) to create high quality 3D graphics of your molecules
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Edit your spectra
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A large vector graphic glassware library
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A large vector color BioArt library
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Build reactions and schemes
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The many powerful widgets
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ChemDraw file support is very thorough (ChemDraw left, ChemDoodle right; ChemDraw does not display margins)
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Even ChemDraw shapes are well supported (ChemDraw left, ChemDoodle right; ChemDraw does not display margins)
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General preferences
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File saving preferences
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Styles preferences

Try ChemDoodle 2D before you buy

A free trial for ChemDoodle 2D lasts for 14 days with some features restricted. The trial is not an obligation and we require no identifying or financial information to start a trial. After 14 days, the trial will no longer open. Our free trials are only for evaluation purposes and any output from the trial will contain a watermark and is copyright of iChemLabs.

To start your trial, simply download ChemDoodle 2D for your operating system below, install and open it. Then accept the EULA. The next page will ask for a license code, instead click the Free Trial button to begin.

When you are ready, you may purchase a ChemDoodle license here:

Version 10.0.1

Version History

SHA256:
2c9f49e00b1655f1a71d7e328d7e55b8401358ad3c4d3821279327319fdacf9b
SHA256:
ed479b7b3c3b38d608e05d933af1abc138bff04acb11c3c67f47465ee6b1f9ad
SHA256:
8c8131407d4a27c5a22087900b530148723845b33ad4f857633be891c26a812c

System Requirements

  • Windows Vista/7/8/10+, macOS 10.11+ (El Capitan, Sierra, High Sierra, Mojave, Catalina or more recent), or Linux.
  • A 64 bit system is required (all modern systems are 64 bit).
  • A minimum of 1GB of memory.