ChemDoodle 2D

2D Chemical Drawing, Publishing and Informatics

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  • “I am a patent attorney and chemist who has become quite beholden to ChemDoodle, particularly the newest version (I've been around since Version 5 or 6, but this thing has gone from great for the price to amazing). Thank you and, indeed, great product!”
    Dinsmore & Shohl LLP
  • “What can I say, above and beyond!!!! ... we are actively recommending the product.”
    CS Regulatory Ltd
  • “I think your program is superior to ChemDraw.”
    Southern Illinois University Edwardsville
  • “ChemDoodle has been a godsend this year.”
    Holmdel High School
  • “Being a mac user I couldn't use chemsketch; found chemdoodle and love it, intuitive to use as well!”
    University of Nottingham
  • “ChemDoodle is an amazingly affordable alternative to ChemDraw. For a fraction of the price, I can get the functionality I need to communicate with my colleagues.”
    Dymax Corporation
  • “ChemDoodle really is a lifesaver - no other chemical structure drawing program on the Mac comes even close...”
  • “Opened my ChemDraw files nicely; intuitive interface. Very smooth operation.”
    Cornell University
  • “I loved the easy-to-use interface; it made drawing molecules and reactions quick and fun!”
    California Polytechnic State University, SLO
  • “This is one of the best chemical drawing programs I have ever used. It is really easy to navigate and create structures. Much better than competitive programs and does not seem bloated and slow.”
    Castech Laboratories LLC
  • “Chemdoodle is very user friendly. I liked the fact that I could draw chem equations easily and without much frustration. Great application.”
    South Texas College
  • “I really like the intuitive feel, not to mention all of the neat widgets, of this program! I've been on a hunt for new chemical drawing software ever since I left my last institution where we had a ChemDraw site license. I've only played around with this software for a couple of hours, but I can already tell that this program is well on its way to blowing all of the other contenders out of the water. Well done guys!”
    Lynchburg College
  • “I've been teaching organic chemistry for 22 years, and have seen a lot of chemical drawing programs. This one is exceptional and I will be recommending this one to my students!”
    Red Deer College
  • “The program is brilliant, very useful for showing NMR to my students.”
    The Royal Latin School
  • “Chemdoodle is excellent, amazing and just unbelievably cheaper than Chemdraw ultra. It is very useful I really liked it and I am going to recommend it to everyone.”
    University of Tasmania
  • “Thank you for giving us a great alternative to ChemDraw! I am using ChemDoodle exclusively now.”
    Temple University
  • “Many thanks for the quick response, and for a feature-rich piece of software that allows us at cash-strapped state schools to make the nice structures we remember from back when we had site licenses for chemdraw. ChemDoodle kicks butt, and I will spread the gospel to my colleagues!”
    University of Missouri, Kansas City
  • “Wow! ChemDoodle is such a fantastic chemical drawing software package. Easy to use and PACKED with features it is such a bargain compared to the alternatives. The interface is intuitive and the User Guide is easy to read (I especially enjoy it being a searchable pdf). I've recommended this software to colleagues and will continue to do so. The more features I learn how to use the more I like it! Superb job!”
  • “ChemDoodle is brilliant! w/ the search option, I can draw Taxol and predict its NMR in 30 secs.”
    Aachen University
  • “I am impressed by the beautiful graphics of this software, and the outstanding operability.”
    Tokyo University of Science
  • “I really love your software and so do my students. We also really like the iPhone app - use it a lot in the Organic Lab I teach.”
    University of St. Thomas
  • “I would strongly recommend ChemDoodle. I find it better than ChemDraw or ISISDraw.”
    Max-Planck Institute
  • “I am lost without ChemDoodle.”
    University at Buffalo
  • “Just want to say this is a great alternative to Chemdraw.”
    University of Leeds
  • “I love the program and the app. Goodbye ChemDraw...finally!”
    SUNY Oneonta
  • “It is impressive. I love it. Many thanks.”
    Coatesville VA Medical Center
  • “Thanks again for making this software available for Linux, you are doing a really good job and the Linux users really appreciate your effort.”
    Cranfield University
  • “The MolGrabber widget has already saved my life and the appearance styling features are outstanding for presentations... yeehaw :)”
  • “Beautiful program, congratulations!”
    L'Université de Genève
  • “I just wanted to say thank you for your excellent customer service and responsiveness. If only all software companies operated this way!”
    Texas A&M
  • “ChemDoodle is really great. In fact, I don't miss anything I know from ChemDraw.”
    Kantonsschule Freudenberg
  • “You really did a very good job with regard to v7. I would especially commend ChemDoodle 3D, which is georgeous, simple for use, great performance, well organized, smoothly working, with a lot features included. The overall picture is breathtaking.”
    Lek Pharmaceuticals D.D.
  • “My compliments on version 7. Much cleaner and the UI is more intuitive. This makes the features easy to navigate to, but they remain compartmentalized. The glassware drawings has always been a nice feature, and I am happy to see it has been expanded from the version 5 I used to have. I will give a presentation at my next department meeting, as the common mythology is that NOTHING is as good as ChemDraw. I believe this version will push the burden onto ChemDraw supporters to provide evidence as to what amazing feature it has that this package cannot go toe-to-toe with.”
    Monsanto Company
  • “I started using ChemDraw back in 1990 or 1991 (on an original Macintosh), back when their price was reasonable, and I was beginning to despair of finding a reasonably priced alternative that was as easy to use. I am glad I found ChemDoodle!!”
    Naval Academy Preparatory School
  • “We like the look and feel to the software and are really happy that we ended up with ChemDoodle and not some other competitor to ChemDraw. The most important part for nearly all of us was, that within 3 minutes we were able to draw molecules the way we wanted them to be drawn! Also as I already told you, we tested a few things and nothing came close to ChemDoodle, as it exceeds ChemDraws capabilities in a lot of areas (Style-settings, responsiveness of the GUI, drawing options, customization).”
    TU Wien

Main Features

ChemDoodle 2D contains thousands of chemistry features, helping you produce the highest quality graphics and saving you hours of work.

  • 2D Graphics

    The best graphics in chemistry

    • Pixel Perfect

      We spend a very long time scrutinizing the graphics output in ChemDoodle. The software automatically orients bonds in the correct directions, merges bond strokes together, places attributes in the best locations and automatically makes smart decisions that lead to the most beautiful and appealing images. Of course, you can always override the software to your preference.

    • Fully Customizable

      Every component of the graphic is fully customizable. Whether you are looking to control bond widths, arrowhead sizes or shape transparency and color; you are in control.

    • 24 Bond Types

      Represent chemical structures with the widest range of chemical bonds avialable in any software tool. From standard integer bonds, to specialty bonds like ionic and covalent, you can accurately depict any structure. All of the bonds orient themselves and merge together for the most aesthetic graphics.

    • Bond Stroke Merging

      In other programs, you will see disconnects where bonds meet, or a heavy reliance on rounded bond ends. In ChemDoodle, all of the bonds merge together for the most aestheic figures.

    • Advanced Labels

      Formatted atom labels allow you to clearly represent chemical entities as text and create concise, professional graphics.

    • Full Unicode Support

      Any characters supported by your fonts are available over the entire unicode range. Quick access to chemically relevant symbols is provided through the Symbols widget.

    • Atomic Notations

      ChemDoodle is the only chemical drawing tool to contain superscript and subscript merge formatting in text fields to easily create atomic notations and other chemical text.

    • Attributes

      Render charges, radicals and electrons, dipole moments, asterisks, tags and custom attributes on your structures, with full control over how they render.

    • Orbitals

      Atomic and molecular orbital graphics are easily added to figures. These are completely customizable just like the rest of ChemDoodle, so you can control color, stroke styling, fill type and more!

    • Highlights

      Easily highlight parts of your structures for emphasis and attention.

    • Lewis Dot Structures

      ChemDoodle provides you with all the tools to build perfect figures of Lewis Dot Structures. Draw them yourself, or have ChemDoodle automatically create the Lewis Dot Structures for you!

    • Perspective Structures

      Easily create 3D effects in figures by using protruding and bold bonds. ChemDoodle will automatically merge their strokes for an optimal appearance. Bonds in the foreground will buffer intersecting bonds in the background.

    • Stroke Styling

      Choose from 7 different stroke styles to add a bit of character to your figures (Basic, Bristle, Brush, Charcoal, Scribble, Slant, Wobble). Perfect for use in group meetings and in presentations.

    • Shapes

      Draw rectangles, ovals, arcs, lines, brackets, Bézier curves, rulers, and more. And of course, all of the shapes are fully stylable.

    • Tables

      Tables are very powerful shapes for creating organized groupings of content in grid patterns. You can control the table grid and its formatting as well as the content that appears within each table cell and cell formatting. Tables can be drawn in several styles and are defined and controlled by an intuitive anchor box set that provides instant feedback for edits you may want to perform. Rowspans, colspans, padding and alignment are supported. Tables can be fit to contained content. This is a great way of creating really attractive and informative figures of data.

    • TLC Plates

      Draw thin layer chromatography plates using the TLC Canvas widget.

  • Drawing

    A powerful interface to quickly complete your work

    • Intuitive Controls

      ChemDoodle’s drawing controls are made to clearly model the atoms and bonds they manage. Copious visual feedback is provided. There are also many options for customizing the drawing tools to your preference, including for accessibility concerns.

    • Measured Drawings

      ChemDoodle will help guide your drawing to create the most aesthetic figures using a feature we call the "Optimize Zone" for standard bond angles and lengths. Just move your mouse out of the zone to override it.

    • Chemical Labels

      In addition to the standard elemental labels, you can input any custom label you desire. ChemDoodle will automatically chemically interpret and format labels. You can also directly control text formatting. Labels can be expanded to full atom models and full atom models can be automatically collapsed into concise labels based on your abbreviation library or to a custom label.

    • Condensed Labels

      Abbreviations and compound labels like "COOH" and "Ph", as well as formulae can be expanded to quickly build and work with complex chemical structures. You can define your own custom abbreviations to be used in ChemDoodle.

    • Custom Element Color Sets

      In addition to the predefined Jmol, Rasmol, PyMOL and CDK color sets, you can also manually define your own elemntal color set to apply to molecule rendering.

    • Automatic Atom/Bond Tagging

      If you need to tag atoms or bonds by increments, ChemDoodle provides powerful tools to do this. Simply click on the atom or bond to tag them and the next tag is automatically incremented. Tag by alphabet, number, roman numeral or greek letter.

    • Auto-layout of Attributes

      ChemDoodle will automatically place your charges, radicals, stereocenter labels and other attributes for you in an aesthetic manner. You can override these decisions at any time by holding down and dragging the mouse during placement.

    • Arbitrary Ring and Crown Ethers

      In addition to standard ring tools and templates, ChemDoodle provides special arbitrary ring and crown ether tools for quickly building advanced ring systems.

    • Templates

      Quickly build structures using our built-in template libraries, or create your own templates. The Templates widget organizes the templates for you.

    • Carbon Nanotube Builders

      Several tools are provided to help you quickly build complex 3D geometries, including carbon nanotube and prism builders. Armchair, zigzag and chiral nanotubes can be built. Use the Rotate in 3D tool to change the 3D perspective of the drawn structure.

    • Structure Cleaning

      Complex algorithms have been implemented to automatically lay out chemical structures aesthetically. Select only part of a structure to clean only that part, leaving the remaining structure untouched.

    • Database Lookup

      Search databases (PubChem, ChemSpider, ChemExper) for chemical structures and drag them right into your 3D scene using the MolGrabber widget.

    • and so much more...

      There are so many tools in ChemDoodle for working with chemical graphics, including alignment and distribution functions, bond adjustment features, action tracking, transforms and more.

  • IUPAC Naming

    Industry leading IUPAC naming algorithms

    Accurate Language

    Our algorithms name molecules naturally and accurately, down to the character and formatting. If you find any problems, simply contact us with the structure so we can correct it.

    Broad Scope

    The entire history of the IUPAC nomenclature library is used in our development. The majority of the periodic table is handled.


    Over 40 options for customizing how names are generated, or to switch between various IUPAC rules.

    Auto-updating Labels

    Display IUPAC names for your structures that automatically update as you draw them. You can even display IUPAC locants on your structures to help with descriptions.

    Name to Structure

    IUPAC names can be parsed into structure representations as well.

  • Cheminformatics

    Chemical intelligence essential to every chemist

    • Implicit Hydrogens

      Implicit hydrogens will be added for you to your drawings. You have the ability to turn them off for single atoms, globally or override them as appropriate.

    • Bond Detection

      Automatically detect bonds in chemical files that don't contain bond data.

    • Ring Perception

      Calculate and depict ring systems in your structures, including the Smallest Set of Smallest Rings (SSSR), the Euler Facet Ring Set, and the Hanser Ring Set.

    • Aromaticity

      Detect the aromaticity and anti-aromaticity of your rings and display the number of pi electron contributors. You can also force aromatic ring recognition using all resonance bonds. Tools are available to switch your figures between Kekulé, delocalized and circle forms.

    • Kekulization

      Automatically produce a Kekulé structure will alternating single and double bonds from a single bond skeleton or any resonance system. This is useful when dealing with large, embedded, aromatic ring systems.

    • Stereochemistry

      Perceive stereochemistry for drawn 2D structures. CIP stereochemistry is determined for chiral centers and double bonds using our advanced and accurate CIP algorithms. Common cis/trans stereochemistry can also be determined for double bonds.

    • Enhanced Stereochemistry

      When you draw a stereochemical configuration for a chiral center in ChemDoodle, it is recognized by the software exactly as drawn, being one of two enantiomers. In certain cases, you may wish to define a current chiral center as one configuration or the other, or as a mixture of both (and). This can be defined using the enhanced stereochemistry features in ChemDoodle. You may then output this information into several file formats for use by compatible registration and search engines, for instance.

    • Repeat Units

      Repeat units (aka repeat groups or repeating brackets) are used to define linearly repeating substructures in molecules. A repeat unit consists of a pair of square brackets denoting the substructure to be repeated and a repeat value defining how many times the substructure is repeated. Most conveniently, when properly defined in chemical structures in ChemDoodle, repeat units are automatically recognized, evaluated and expanded so you can quickly draw complex structures and perform cheminformatics tasks such as calculating molecular masses and formulas. This is very convenient for oligomers and polymers.

    • 3D Coordinate Generation

      Generate 3D coordinates for your drawn structures using a template method or Universal Force Field (UFF) optimization.

    • Descriptors

      Calculate dozens of descriptors for structures, including masses, formulae, volumes, physical properties, topological indexes, counts, bioactivity filters and more.

    • Elemental Analysis

      Use the Elemental Analysis widget to calculate molecular masses, elemental analysis and isotopic distributions for structures as you draw them. Select entire complexes to calculate bulk properties.

    • Chemical Warnings

      ChemDoodle will double check your work for you and notify you when it finds chemistry issues, such as overvalanced atoms, incorrectly drawn stereocenters, or partially intersecting repeat units.

    • Elemental Database

      ChemDoodle contains an entire elemental database. Most of the calculations performed by ChemDoodle use this data. The data is kept relevant and referenced and includes many elemental properties such as electronegativites, radii, thermodynamic properties, years of discovery and more. Databases of ionization energies and isotopes are also provided. You may view this data at any time in the View menu.

    • Periodic Table

      A fully interactive periodic table is provided for visualization and reference. You can even customize it and print it out!

    • SciFinder Integration

      Initiate CAS SciFindern queries and gain access to a history of chemical information right from ChemDoodle. Draw your query in ChemDoodle and search SciFindern by Substances, Suppliers, Reactions or References. A SciFindern account is required.

    • Google Patents Integration

      Google Patents searching is integrated. You may perform structure, substructure and similarity searching into the Google Patents and non-patent literature databases at Google using structures drawn in ChemDoodle.

    • References

      All of the resources we use to develop the algorithms in ChemDoodle or the choices we make for the software are documented in the Help menu. This way you can evaluate the quality of our work.

  • Reactions

    Reaction tools make for fast graphics and immediate results

    • Arrows

      Arrows are essential in chemical graphics for many reasons, the most important being for reaction and mechanism diagrams. Arrows are so important that, in ChemDoodle 2D, they have their own unique toolbar palette. These tools allow you to quickly draw various types of arrows, both straight and in arcs. Special arrow type templates are also provided, such as bold, equilibrium and retrosynthetic arrows. Other types of paths, such as polylines and bezier curves can also be used for arrows.

    • Electron Pushing

      ChemDoodle 2D provides unique tools to automatically render single electron, electron pair and bond forming pushing arrows based on an starting and ending atom or bond. Quickly create advanced mechanism drawings.

    • Styling

      Arrows and arrowheads are completely customizable, just like everything else in ChemDoodle 2D. Change sizes, fills, colors and more. You may also change the arrow stroke to create a wavy photon arrow, or include a no go slash or cross.

    • Reaction Definitions

      You can manually define reactants and products, or have ChemDoodle 2D automatically infer reaction components based on their locations around an arrow.

    • Synthesis and Retrosynthesis Tools

      ChemDoodle 2D contains convenient tools for building reactions based on bond breaking and formation. Simply drag the tool over the desired bonds and the appropriate reactions will automatically be generated for you.

    • Automatic Layout

      Reactions can be automatically laid out for you, to achieve the most aesthetic figures. Reactions that are very wide will be stacked appropriately.

    • Balancing

      Complete reactions can be balanced by ChemDoodle 2D, either when drawn using structures and arrows, or typed as a reaction equation. ChemDoodle 2D will be able to balance any reaction equation that can be balanced. For infinitely irreducible solutions, a proprietary algorithm that minimizes positive integers for coefficients will be determined to balance your equation.

    • Stoichiometry

      ChemDoodle 2D provides an industry leading stoichiometry table. This stoichiometry table is a form where you input theoretical and experimental values from your experiment and you will get accurate calculations for your input and results. ChemDoodle 2D's stoichiometry tables are fully chemically aware and are self-calculating. Input reactions are automatically balanced (however you can override these stoichiometric ratios with the Equivalents row) and the limiting component is automatically inferred based on the input values. ChemDoodle 2D enforces the credibility of the calculations for the entire table, and will even warn you if your input is suspicious, for instance, if you have a percent yield greater than 100%.

  • Spectroscopy

    Easily create figures with both structures and spectra

    JCAMP-DX Format

    Read mass spectrometry (MS), nuclear magnetic resonance spectroscopy (NMR), infrared spectroscopy (IR) and other spectra from JCAMP-DX files. Multiple spectra are also recognized from the advanced JCAMP NTUPLES specification.


    Completely edit the domain and range perspectives for your spectra. Include integration lines and grids. Format titles and then add annotations with shape tools.


    Simulate both 1H and 13C NMR spectroscopy as well as mass spectrum isotopic distributions. The NMR SignalSeek widget will also provide you with structure-spectrum correlations and further insight into the simulation. You can completely customize the settings for the simulations. Fine tune your analysis with the Multiplet Tool, which provides powerful functions for simulating and multiplet patterns.

    Mass Fragmentation Tools

    Use simple tools to quickly split bonds and calculate molecular masses for the fragments.

  • Vector Art

    Hand-drawn scientific vector art libraries are included

    Laboratory Art

    Hundreds of different, hand-drawn, glassware images and other laboratory art are included to create very complex laboratory setups. Find helpful graphics, including laboratory appliances and safety symbols. Liquid fill colors can be controlled. Use thick Bézier curves for tubing.


    Full color and skillfully drawn vector graphics for illustrating cells, anatomy, animals, space and more.

    Infinitely Scalable

    The vector art is fully scalable, so each image can be resized or printed without any loss of resolution, leading to the most professional diagrams.

  • Publishing

    Maximize your visibility with ChemDoodle's publishing features

    • Style Sheets

      ChemDoodle provides a number of predefined chemical style sheets to create styled graphics specifically for certain journals, including Nature and ACS Document 1996. You can also create and share your own style sheets to make creating books and other projects easier when groups are involved.

    • Chemical Files

      Read and write many popular chemical file types for working with the applications you use:

      ACD/ChemSketch Documents (.sk2), ChemDoodle Documents (.icl), ChemDoodle 3D Scenes (.ic3), ChemDoodle Javascript Data (.cwc.js), CambridgeSoft ChemDraw Exchange (.cdx), CambridgeSoft ChemDraw XML (.cdxml), Crystallographic Information Format (.cif), CHARMM CARD File (.crd), ChemAxon Marvin Document (.mrv), Chemical Markup Language (.cml), Daylight SMILES (.smi, .smiles), IUPAC InChI (.inchi), IUPAC JCAMP-DX (.jdx, .dx), ISIS Sketch File (.skc), ISIS Sketch Transportable Graphics File (.tgf), MDL MOLFiles, both V2000 and V3000 connection tables (.mol, .mdl), MDL SDFiles (.sdf, .sd), MDL RDFiles (.rdf, .rd), MDL RXNFiles, both V2000 and V3000 connection tables (.rxn), MMI SketchEl Molecule (.el), Molinspiration JME String (.jme), RCSB MacroMolecular Transmission Format (.mmtf), RCSB Protein Data Bank Files (.pdb, .ent), Schrödinger MacroModel (.mmd, .mmod), Schrödinger Maestro (.mae), Standard Molecular Data (.smd), Tripos Mol2 (.mol2, .ml2, .sy2), Tripos Sybyl Line Notation (.sln), Beilstein ROSDAL (.ros), XYZ Files (.xyz)

    • Line Notations

      Quickly analyze chemical line notations from websites and generate them for searches using the Line Notation Pad widget.

    • Bitmap (Raster, Pixel) Images

      Write a large number of bitmap (also known as raster or pixel) images for use with other applications. Some formats have additional options, such as controlling output resolution in PNG, JPEG, and TIFF images.

      1. CompuServ Graphics Interchange Format {.gif}
      2. Joint Photographic Experts Group {.jpg, .jpeg, .jpe, .jfif, .jfi, .jif}
      3. Microsoft Bitmap {.bmp, .dib}
      4. Portable Network Graphics {.png}
      5. Tagged Image File Format {.tiff, .tif}
      6. UNIX Portable PixMap {.ppm, pnm, pbm, pgm}
      7. Wireless Bitmap {.wbmp}

    • Scalable Vector Graphics

      Write a large number of vector graphics formats for use with other graphics applications when scalability is required. Most of the vector formats allow for text to shape conversion (compatibility) or preserving text output (for future editing, such as in LaTeX document creation). Most of the vector formats also allow embedding of chemical data to be recovered later.

      1. Adobe Portable Document Format {.pdf}
      2. Encapsulated Postscript {.eps, .epi, .epsi, .epsf}
      3. Macintosh Vector Pict {.pict}
      4. OpenDocument Graphics {.odg}
      5. Web Scalable Vector Graphics {.svg, .svgz}
      6. Windows Enhanced Metafile {.emf}

    • Advanced Image Sizing

      By default, ChemDoodle will automatically size output images to fit content, but you may override this behavior to any custom image size while instructing ChemDoodle to scale or buffer your drawings. A convenient preview is provided when saving images to visualize output size and how your drawing will fit.

    • Web Components

      Produce 2D ChemDoodle Web Components, which are high-quality, interactive, HTML5 components for websites and web apps that work in Microsoft Edge, Mozilla Firefox, Google Chrome, Apple Safari and Opera, and even on Mobile Safari on iOS and Chrome for Android.

    • Twitter Integration

      Quickly tweet your selected content from ChemDoodle.

  • Recovery

    Reclaim your chemical data

    Chemical Files

    Read in chemical files from over 30 formats created by other chemistry software. More than just the molecules are recovered, including reactions, spectra, arrows, shapes and more. Thorough support for MDL, SMILES, CDX, CDXML files and more.

    Round-trip Editing

    ChemDoodle will paste embedded data into 3rd party applications, like a word processor. So, if you paste a ChemDoodle figure into Microsoft® Word, you will later be able to copy that ChemDoodle figure from Microsoft Word and paste back into ChemDoodle for further editing. Supported on Windows, macOS and Linux, but limited to the operating system the figure was embedded on.

    Chemical Data Recovery

    ChemDoodle can recover chemical data and figures pasted from other chemical software into 3rd party applications, without needing the other chemical program.

    Microsoft Office Recovery

    If you no longer have access to Microsoft Office or the original operating system the chemical figure was embedded on, ChemDoodle can search your Microsoft Office files and recover the chemical drawings (ChemDoodle and 3rd party) for extraction and further editing.

    Chemical Image Recovery

    ChemDoodle contains an advanced feature to completely rebuild chemical drawings from images of molecules, with no chemical data provided. The recovered chemical drawings can be used for further editing or analysis. Chemical Image Recovery (CIR) is also known as Optical Structure Recognition (OSR).

    Microsoft is a registered trademark of Microsoft Corporation.

  • Universality

    Regardless of what technologies you need, ChemDoodle is there

    • Operating Systems

      Fully supported on Windows, macOS and Linux.

    • High DPI Support

      Full support for high resolution displays, such as Retina Macs and the Microsoft Surface Pro.

    • Accessibility

      Control interface colors, interface font sizes, define cursors and a cursor left-handed and right-handed mode make it comfortable for most users to use the software. You can also fully define all of the menu item accelerators (except the ones forced by the operating system) and tool shortcuts.

    • Word Processors

      Paste scalable vector graphics into your favorite word processors, including Microsoft Office, Apple iWork and OpenOffice.

    • Round-trip Editing

      Round-trip editing allows you to insert content into 3rd party applications, and then place that same content back into ChemDoodle from that 3rd party application for further editing. Round-trip editing is supported on Windows through OLE, macOS via PDF and on Linux with OpenOffice.

      NOTE: It takes two applications to work together for round trip editing. While ChemDoodle provides functionality for round trip editing, the other application you want to round trip with may not support round trip editing. Other applications that do support round trip editing may remove round trip editing functionality at any time and without the consent of iChemLabs.

    • Quicklook Plugin

      A Quicklook plugin for macOS allows you to preview all of the chemical formats ChemDoodle understands conveniently in Finder. Not on Mac? No worries, ChemDoodle’s file chooser contains previews on all operating systems.

    • Search for Structures

      Search your computer and attached storage devices for chemical structures using the Search widget.

    • Browsers

      Produce interactive HTML5 components that work in Microsoft Edge, Mozilla Firefox, Google Chrome, Apple Safari and Opera, and even on Mobile Safari on iOS and Chrome for Android.

    • Mobile Devices

      A ChemDoodle license includes access to our ChemDoodle Mobile app companion for iOS (iPod/iPhone/iPad), Android and other mobile devices.

    • 3rd Party Integration

      ChemDoodle works with several partners to help you improve your workflow. These partners include databases like PubChem, ChemExper and ChemSpider, ELNs such as LabArchives and social networking services like Twitter.

    • Continuously Developed

      We are always adding new features, and our customers continuously enjoy new updates with great new innovative solutions and tools that they have requested. Your license entitles you to all updates.

    • Thorough Documentation

      A thorough user manual is free to download. It is in PDF format, fully searchable with a fully linked table of contents and index.


Windows interface
macOS interface
Linux interface
Paste scalable vector graphics into and round trip editing with Microsoft Office (Windows, Mac OS X) see features
Paste scalable vector graphics into and round trip editing with Apple iWork and Microsoft Office (Mac OS X) see features
Paste scalable vector graphics into and round trip editing with OpenOffice and LibreOffice (Linux) see features
ChemDoodle contains dozens of options to control IUPAC naming output
ChemDoodle works with ChemDoodle 3D (included with your ChemDoodle license) to create high quality 3D graphics of your molecules
Edit your spectra
A large vector graphic glassware library
A large vector color BioArt library
Build reactions and schemes
The many powerful widgets
ChemDraw file support is very thorough (ChemDraw left, ChemDoodle right; ChemDraw does not display margins)
Even ChemDraw shapes are well supported (ChemDraw left, ChemDoodle right; ChemDraw does not display margins)
General preferences
File saving preferences
Styles preferences

Try ChemDoodle 2D before you buy

A free trial for ChemDoodle 2D lasts for 14 days with some features restricted. The trial is not an obligation and we require no identifying or financial information to start a trial. After 14 days, the trial will no longer open. Our free trials are only for evaluation purposes and any output from the trial will contain a watermark and is copyright of iChemLabs.

To start your trial, simply download ChemDoodle 2D for your operating system below, install and open it. Then accept the EULA. The next page will ask for a license code, instead click the Free Trial button to begin.

When you are ready, you may purchase a ChemDoodle license here:

Version 11.7.0

Version History


System Requirements

  • Windows Vista/7/8/10/11+, macOS 10.11+ (El Capitan, Sierra, High Sierra, Mojave, Catalina, Big Sur, Monterey or more recent), or Linux.
  • A 64 bit (x86_64 or Apple Silicon) processor is required.
  • A minimum of 1GB of memory.